Table 3.
Non-hematologic Toxicities
| Toxicity | Grade 1 N (%) |
Grade 2 N (%) |
Grade 3 N (%) |
Grade 4 N (%) |
Grade 5 N (%) |
|---|---|---|---|---|---|
| Dyspnea | 2 (33.3%) | 2 (33.3%) | 1 (16.7%) | ||
| Respiratory Failure | 1 (16.7%) | 1 (16.7%) | |||
| Upper Respiratory Infection | 1 (16.7%) | ||||
| Cough | 1 (16.7%) | 1 (16.7%) | |||
| Pneumonia | 1 (16.7%) | ||||
| Hallucinations | 1 (16.7%) | ||||
| Dehydration | 1 (16.7%) | 1 (16.7%) | |||
| Hypotension | 1 (16.7%) | 1 (16.7%) | |||
| Dermatology, Other (Heating pad burn) | 1 (16.7%) | ||||
| Pain | 1 (16.7%) | 1 (16.7%) | 1 (16.7%) | ||
| Peripheral Neuropathy | 1 (16.7%) | ||||
| Hyperglycemia | 1 (16.7%) | ||||
| Infection | 1 (16.7%) | ||||
| Sore throat | 1 (16.7%) | ||||
| Flu-like symptoms | 1 (16.7%) | ||||
| Fatigue | 1 (16.7%) | 4 (66.7%) | |||
| Arthralgia | 1 (16.7%) | ||||
| Headache | 1 (16.7%) | ||||
| Fever | 2 (33.3%) | ||||
| Decreased level of consciousness | 1 (16.7%) | ||||
| Nausea/Vomiting | 1 (16.7%) | ||||
| Hyponatremia | 1 (16.7%) | ||||
| Hypoxia | 1 (16.7%) | ||||
| Syncope | 1 (16.7%) | ||||
| Rash | 1 (16.7%) | ||||
| Injection site reactiona | 1 (16.7%) | ||||
| Infection, Other (Lip)b | 1 (16.7%) | ||||
| Dizziness | 1 (16.7%) | ||||
| Constipation | 1 (16.7%) | ||||
| Hypoalbuminemia | 1 (16.7%) |
aAttributed to DRibble vaccine
bAttributed as unlikely related to DRibble vaccine
All other toxicities were attributed as unrelated to DRibble vaccine, but were considered related to docetaxel or underlying disease