. 2017 Dec 19;5:17042. doi: 10.1038/boneres.2017.42

Table 1. Micro-CT measurements of bone parameters at the metaphysis (secondary spongiosa) of the tibia in control and mTBI mice at 2, 8 and 12 weeks post impact.

Bone parameters	Control	Weight drop height/m
		0.5	1.0	1.5
2 weeks post impact
BV/mm³	0.16±0.004	0.14±0.002	0.14±0.003	0.12±0.002^A
BV/TV	0.19±0.003	0.17±0.002	0.17±0.003	0.16±0.003^A
Tb.N/mm⁻¹	6.11±0.09	5.86±0.05	5.85±0.07	5.71±0.06
Tb. Th/mm	0.048±0.000 2	0.046±0.000 2	0.047±0.000 2	0.045±0.000 2^A
Tb. Sp/mm	0.17±0.002	0.17±0.001	0.16±0.003	0.18±0.001
Trabecular bone density (mg·cm⁻³)	164±1.93	142±3.0	151±2.29	139±1.06^A
Cortical bone density (mg·cm⁻³)	587±1.24	586±2.68	594±2.29	575±1.34

8 weeks post impact
BV/mm³	0.18±0.002	0.13±0.003^A	0.17±0.001	0.15±0.002^A
BV/TV	0.21±0.003	0.17±0.003^A	0.22±0.002	0.19±0.003^B
Tb.N/mm⁻¹	5.79±0.05	5.53±0.03	5.83±0.04	5.48±0.01
Tb. Th/mm	0.05±0.000 4	0.04±0.000 4^A	0.05±0.000 2	0.04±0.000 5
Tb. Sp/mm	0.16±0.001	0.17±0.001	0.16±0.001	0.17±0.005
Trabecular bone density (mg·cm⁻³)	179±2.30	153±2.82^A	177±1.53	159±2.43^A
Cortical bone density (mg·cm⁻³)	734±2.43	693±2.25^A	697±2.75^A	733±4.78

12 weeks post impact
BV/mm³	0.15±0.000 3	0.10±0.002^A	0.11 ±0.000 3^B	0.11±0.002^A
BV/TV	0.19±0.005	0.14±0.002^A	0.16±0.003^B	0.15±0.002^A
Tb.N/mm⁻¹	5.32±0.08	4.80±0.037^B	4.90±0.043	4.89±0.03
Tb. Th/mm	0.054±0.000 2	0.04±0.000 5^A	0.05±0.000 4	0.050±0.000 2^A
Tb. Sp/mm	0.19±0.002	0.20±0.002	0.20±0.002	0.20±0.001
Trabecular bone density (mg·cm⁻³)	183±3.20	141±2.59^A	152±2.69^A	148±2.14^A
Cortical bone density (mg·cm⁻³)	827±1.78	815±2.68	815±1.90	810±1.46^A

Abbreviations: Micro-CT, micro-computed tomography; mTBI, mild traumatic brain injury.

Values are mean±s.e. n=7–10, ^AP<0.05 vs control and ^BP=0.07 vs control.