. 2017 Dec 19;12:184. doi: 10.1186/s13023-017-0740-z

Table 1.

Mitochondrial complex activities at baseline, pre-training and post-training in Huntington disease (HD) patients and healthy controls

	HD (n = 13)			Controls (n = 11)
	Baseline	Pre-Training	Post-Training	Pre-Training	Post-Training
Absolute values
Citrate synthase (mU·mU⁻¹ Protein)	150 ± 42	141 ± 34	163 ± 47^{##, †}	164 ± 65	198 ± 67^{##, †}
Complex I (mU·mU⁻¹ Protein)	35 ± 11	28 ± 9*	26 ± 7^†	36 ± 15	33 ± 13^†
Complex II (mU·mU⁻¹ Protein)	40 ± 9	38 ± 11	37 ± 11	37 ± 14	44 ± 16
Complex III (mU·mU⁻¹ Protein)	123 ± 35	114 ± 32	137 ± 51^##	122 ± 46	154 ± 55^##
Complex IV (mU·mU⁻¹ Protein)	165 ± 39	151 ± 56	131 ± 47	142 ± 50	164 ± 51
Complex V (mU·mU⁻¹ Protein)	75 ± 25	72 ± 24	91 ± 29^#	69 ± 29	80 ± 26^#
SCCR (mU·mU⁻¹ Protein)	34 ± 11	35 ± 8	49 ± 25^##	35 ± 14	46 ± 14^##
NCCR (mU·mU⁻¹ Protein)	28 ± 15	29 ± 12	35 ± 13	26 ± 11	30 ± 10
Relative values
Complex I (mU·mU⁻¹ CS)	0.241 ± 0.044	0.201 ± 0.051*	0.164 ± 0.037^###	0.225 ± 0.049	0.168 ± 0.044^###
Complex II (mU·mU⁻¹ CS)	0.271 ± 0.041	0.269 ± 0.059	0.227 ± 0.038^#	0.232 ± 0.044	0.225 ± 0.043^#
Complex III (mU·mU⁻¹ CS)	0.837 ± 0.158	0.828 ± 0.203	0.846 ± 0.184	0.796 ± 0.087	0.779 ± 0.099
Complex IV (mU·mU⁻¹ CS)	1.124 ± 0.191	1.067 ± 0.300	0.835 ± 0.246	0.871 ± 0.119	0.840 ± 0.133
Complex V (mU·mU⁻¹ CS)	0.507 ± 0.155	0.522 ± 0.168	0.528 ± 0.109^†	0.414 ± 0.074	0.400 ± 0.067^†
SCCR (mU·mU⁻¹ CS)	0.228 ± 0.056	0.253 ± 0.048	0.269 ± 0.095	0.215 ± 0.033	0.236 ± 0.034
NCCR (mU·mU⁻¹ CS)	0.185 ± 0.094	0.209 ± 0.081	0.222 ± 0.120^††	0.145 ± 0.029	0.153 ± 0.016^††

Values are mean ± SD. NCCR, NADH cytochrome c reductase, SCCR, succinate cytochrome c reductase. *P < 0.05, significant different to baseline; ^# P < 0.05, ^## P < 0.01, ^### P < 0.001, significant time effect; ^† P < 0.05, ^† P < 0.01, significant group effect