Table 4.
The interaction effect of body fat percentage change and menopausal status on distant metastasis and all-cause mortality in women with breast cancer (N = 131)
| B (± SE) | Hazard ratio (95% CI) |
p | |
|---|---|---|---|
| Metastasis | |||
| Advanced disease (Stage III) | 2.05 (± 0.49) | 7.80 (3.00–20.28) | < .001 |
| ER positive | 0.87 (± 0.58) | 2.39 (0.76–7.45) | .134 |
| PR positive | −0.75 (± 0.52) | 0.47 (0.17–1.30) | .146 |
| Age | −0.03 (± 0.03) | 0.97 (0.93–1.02) | .235 |
| Regular exercise | 0.01 (± 0.52) | 1.01 (0.37–2.82) | .978 |
| Body fat % change × menopausal status | 0.29 (± 0.11) | 1.33 (1.06–1.66) | .012 |
| Death | |||
| Advanced disease (Stage III) | 3.22 (± 0.79) | 25.09 (5.34–117.89) | < .001 |
| ER positive | 0.41 (± 0.74) | 1.50 (0.35–6.45) | .585 |
| PR positive | −0.77 (± 0.66) | 0.46 (0.13–1.70) | .246 |
| Age | 0.02 (± 0.03) | 1.02 (0.96–1.09) | .555 |
| Regular exercise | −0.32 (± 0.72) | 0.73 (0.18–2.98) | .660 |
| Body fat % change × menopausal status | 0.32 (± 0.15) | 1.18 (1.03–1.86) | .033 |
Body fat % change = body fat percentage at 6 months after surgery minus body fat percentage before surgery
ER estrogen receptor, PR progesterone receptor