Table 1.
Baseline characteristics of the exenatide and metformin groups.
| Parameters | Exenatide (n = 110) | Metformin (n = 120) | P |
|---|---|---|---|
| Age, y | 45.77 ± 10.60 | 48.05 ± 8.04 | 0.097 |
| Gender, males/females, n | 64/46 | 71/49 | 0.880 |
| Overweight/obesity, n | 57/53 | 63/57 | 0.918 |
| Body weight, kg | 78.76 ± 10.01 | 77.98 ± 11.88 | 0.907 |
| BMI, kg/m2 | 27.83 ± 2.38 | 27.57 ± 3.56 | 0.815 |
| TC, mmol/L | 5.21 ± 1.25 | 5.29 ± 1.22 | 0.664 |
| LDL-C, mmol/L | 3.07 ± 0.89 | 3.05 ± 0.90 | 0.864 |
| HDL-C, mmol/L | 1.12 ± 0.43 | 1.24 ± 0.29 | 0.087 |
| TG, mmol/L | 2.07 (1.27–3.99) | 1.93 (1.32–2.75) | 0.235 |
| FBG, mmol/L | 9.34 ± 3.27 | 9.10 ± 1.34 | 0.594 |
| FINS, μIU/mL | 9.50 (5.98–14.37) | 10.14 (5.25–14.94) | 0.337 |
| HbA1c, % | 9.11 ± 1.46 | 9.03 ± 1.18 | 0.230 |
| HOMA-IR | 3.94 (2.47–5.93) | 3.87 (2.27–6.02) | 0.638 |
| HOMA-β | 55.13 (29.64–76.65) | 50.55 (29.80–74.81) | 0.289 |
Data are means ± SD unless indicated otherwise. TG, FINS, HOMA-IR, and HOMA-β are shown as medians (upper and lower quartiles). BMI: body mass index; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; TG: triglyceride; FBG: fasting blood glucose; FINS: fasting insulin; HOMA-IR: homeostasis model assessment of insulin resistance; HOMA-β: homeostasis model assessment of β-cell function.