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. 2017 Dec 19;15:53. doi: 10.1186/s12964-017-0207-9

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — ROC curves for classifying the apoptotic response. Blue: ROC curve for the difference between the initial concentration of PARP and XIAP input; AUC is 0.97. Purple: ROC curve for the initial PARP concentration input; AUC is 0.95. Cyan: ROC curve for the initial XIAP concentration input; AUC is 0.65. All of three AUC values are significantly different than 0.5 (given by the gray dashed line, p < 0.0001), indicating that these inputs are reliable predictors of the cells’ response to TSP1 stimulation