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. Author manuscript; available in PMC: 2017 Dec 19.
Published in final edited form as: J Neurooncol. 2012 Jul 26;110(1):111–118. doi: 10.1007/s11060-012-0943-z

Table 3.

Grade ≥ 3 toxicities associated with sunitinib: AA cohort (n = 14)

Toxicity category Description
(CDUS toxicity type code)
Grade 3
n (%)
Grade 4
n (%)
Grade 5
n (%)
Total grade
3–5
Blood/bone marrow Leukocytes (total WBC) 2 (14.3) 1 (7.1) 3 (21.4)
Lymphopenia 1 (7.1) 1 (7.1)
Platelets 2 (14.3) 2 (14.3)
Constitutional Symptoms Fatigue (asthenia, lethargy, malaise) 1 (7.1) 1 (7.1)
Death Death not associated with CTCAE term—disease progression NOS 1 (7.1) 1 (7.1)
Dermatology/skin Dermatology/skin—other 1 (7.1) 1 (7.1)
Rash: hand-foot skin reaction 2 (14.3) 2 (14.3)
Hemorrhage/bleeding Hemorrhage/bleeding—other 1 (7.1) 1 (7.1)
Overall Maximum toxicity 4 (28.6) 1 (7.1) 1 (7.1) 6 (42.9)