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. 2017 Dec 15;13:1585–1593. doi: 10.2147/TCRM.S151180

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© 2017 Le et al. This work is published and licensed by Dove Medical Press Limited

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Pathological presentations of CMV colitis.

Notes: CMV colitis was diagnosed by both CMV inclusion bodies and positive IHC staining in the colonic tissue. (A) H&E stain (40× objective) showed typical intranuclear (owl’s eye) and intracytoplasmic (eosinophilic punctiform) CMV inclusions within the circles. (B) IHC stain (20× objective) was performed with 1:200 diluted Novocastra™ lyophilized mouse monoclonal antibody against CMV pp65 antigen and showed strong focal CMV immunoreactivity with brownish areas.

Abbreviations: CMV, cytomegalovirus; H&E, hematoxylin and eosin; IHC, immunohistochemistry.