FIGURE 1.
Experimental time line for each mouse. Partial unilateral ureteral obstruction (pUUO) surgery was performed at day 0 (open circle). Magnetic resonance imaging and collection of blood and urine samples were performed 2 days prior to surgery (baseline) and at three separate time points afterwards (filled circles). After imaging on the final day, mice were sacrificed and both kidneys were harvested for immunohistological and biochemical evaluation