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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Acta Biomater. 2017 Jun 3;58:386–398. doi: 10.1016/j.actbio.2017.06.004

Scheme 1.

Scheme 1

Schematic illustration of synthesis, redox-triggered biodegradation and drug release of BA-TPQ-hydrogel cube (BA-TPQ-hydrogel). (1) PEI-coated porous Mn2O3 cubic template; (2) Hydrogen-bonded PMAA/PVPON multilayers inside the pores of the template; (3) Hydrogen-bonded PMAA/PVPON multilayers after template dissolution; (4) Cystamine cross-linked PMAA hydrogel cube; (5) Hydrophobic drug (BA-TPQ) encapsulation in PMAA multilayer hydrogel; (6) Redox-triggered degradation of the hydrogel cube and subsequent BA-TPQ release.