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. 2017 Dec 3;7(12):e018632. doi: 10.1136/bmjopen-2017-018632

Table 1.

Assessment of risk of bias in included studies

Source of bias Macpherson and Lofgren7 Auerbach et al 8 Katz et al 9 Vazirani et al 10
Selection bias
 Randomisation (RCT) Permuted blocks of size 2 and 4, stratified by quartiles of anticipated LoS
 Allocation concealment (RCT) Not reported
 Control for confounders (NRS) Patients sampled at random; propensity score weighting Consecutive patients Regression methods
 External validity (RCT and NRS) Uncertain as study setting was more restrictive than a non-experimental setting Potential unobserved confounding Potential unobserved confounding Potential unobserved confounding
Performance bias
 Blinding of participants and/or investigators (RCT) No
 Measurement of exposure (NRS) No blinding but 5% of medical record abstractions were reviewed for data validity No blinding No blinding
Detection bias
 Blinded outcome assessment (RCT and NRS) No blinding but 100% interobserver and intraobserver agreement* Not reported Not reported Not reported
Attrition bias
 Completeness of follow-up (RCT and NRS) Yes Yes 35 (8.3%) patients with missing medical records Yes

Ellipses indicate not applicable.

*A researcher re-abstracted length of stay data on 10 randomly selected records, and a physician not associated with the study abstracted length of stay from the same 10 records.

LoS, length of stay; NRS, non-randomised studies; RCT, randomised controlled trials.