Fig 4. Increased plasma sCD127 concentrations correlated with IL-7-induced increases in CD8⁺ T-cells in SIV-infected Rhesus macaques.

(A-D) Representative graphs of IL-7-treated animals whose concentration of plasma sCD127 increased with changes in absolute CD8⁺ T-cell numbers in at least one IL-7 cluster during the cytokine treatment time period. (E) In the animal that maintained viral control, plasma sCD127 concentrations did not appear to associate with changes CD8⁺ T-cell numbers. Total number of IL-7-treated animals in which data of absolute T-cells was available: n = 5. The clustered administration of IL-7 is indicated on the x-axis by groups of three arrows.