Fig 5. Increased plasma sCD127 concentrations correlated with IL-7-induced increases in CD8⁺ T-cell subsets in SIV-infected Rhesus macaques.

All CD8⁺ T-cell subsets with statistically significant correlations with sCD127 are graphed here. Increasing concentrations of plasma sCD127 following IL-7 administration were positively correlated with increases in (A) total, (B) naïve T_N, (C) transitional effector memory T_TrM and (D) central memory T_CM CD8⁺ T-cell subsets in SIV-infected, ART-treated Rhesus macaques (Spearman correlation analysis, r- and p-values are indicated on graphs).