Table 4. Univariate and multivariate regression analysis for log MAGE in the DM group.
Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|
Variables | β | SE | P value | β | P value |
Age | 0.003 | 0.001 | <0.01 | 0.003 | <0.01 |
Male | -0.015 | 0.003 | 0.63 | -0.010 | 0.76 |
BMI | -0.005 | 0.003 | 0.08 | - | |
Systolic BP | 0.001 | 0.001 | 0.16 | - | |
HbA1c | -0.001 | 0.008 | 0.88 | - | |
FPG | 0.000 | 0.000 | 0.42 | - | |
HOMA-R | -0.007 | 0.006 | 0.25 | - | |
log Triglyceride | -0.055 | 0.060 | 0.40 | - | |
HDL-C | 0.001 | 0.001 | 0.39 | - | |
LDL-C | 0.000 | 0.000 | 0.35 | - | |
log Creatinine | 0.110 | 0.065 | 0.09 | - | |
Hb | -0.008 | 0.007 | 0.24 | - | |
log BNP | 0.032 | 0.020 | 0.10 | - | |
LVEF | 0.000 | 0.001 | 0.64 | - | |
Epworth Sleepiness Scale score | 0.001 | 0.005 | 0.76 | - | |
AHI | 0.001 | 0.001 | 0.26 | 0.000 | 0.59 |
3% ODI | 0.001 | 0.001 | 0.42 | - | |
Time at SpO2<90% | 0.000 | 0.003 | 0.62 | - | |
log lowest SpO2 | 0.096 | 0.373 | 0.80 | - | |
β-blocker | 0.012 | 0.030 | 0.71 | - | |
Sulphonylurea | 0.007 | 0.045 | 0.89 | - | |
α-glucosidase inhibitor | -0.003 | 0.040 | 0.93 | - | |
Biguanide | -0.088 | 0.038 | 0.02 | -0.040 | 0.28 |
DPP-4 inhibitor | 0.039 | 0.033 | 0.24 | - | |
Insulin | 0.110 | 0.030 | <0.01 | 0.100 | <0.01 |
Other antidiabetic drugs | 0.047 | 0.080 | 0.57 | - |
BMI = body mass index, BP = blood pressure, FPG = fasting plasma glucose, HbA1c = glycated hemoglobin
HOMA-R = homeostasis model assessment ratio, HDL-C = high-density lipoprotein cholesterol
LDL-C = low-density lipoprotein cholesterol, Hb = hemoglobin, BNP = brain natriuretic peptide
LVEF = left ventricular ejection fraction, AHI = apnea-hypopnea index, ODI = oxygen desaturation index
SpO2 = peripheral capillary oxygen saturation, DPP-4 = dipeptidyl peptidase-4