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. 2017 Dec 19;12(12):e0188689. doi: 10.1371/journal.pone.0188689

Table 4. Univariate and multivariate regression analysis for log MAGE in the DM group.

Univariate analysis Multivariate analysis
Variables β SE P value β P value
Age 0.003 0.001 <0.01 0.003 <0.01
Male -0.015 0.003 0.63 -0.010 0.76
BMI -0.005 0.003 0.08 -
Systolic BP 0.001 0.001 0.16 -
HbA1c -0.001 0.008 0.88 -
FPG 0.000 0.000 0.42 -
HOMA-R -0.007 0.006 0.25 -
log Triglyceride -0.055 0.060 0.40 -
HDL-C 0.001 0.001 0.39 -
LDL-C 0.000 0.000 0.35 -
log Creatinine 0.110 0.065 0.09 -
Hb -0.008 0.007 0.24 -
log BNP 0.032 0.020 0.10 -
LVEF 0.000 0.001 0.64 -
Epworth Sleepiness Scale score 0.001 0.005 0.76 -
AHI 0.001 0.001 0.26 0.000 0.59
3% ODI 0.001 0.001 0.42 -
Time at SpO2<90% 0.000 0.003 0.62 -
log lowest SpO2 0.096 0.373 0.80 -
β-blocker 0.012 0.030 0.71 -
Sulphonylurea 0.007 0.045 0.89 -
α-glucosidase inhibitor -0.003 0.040 0.93 -
Biguanide -0.088 0.038 0.02 -0.040 0.28
DPP-4 inhibitor 0.039 0.033 0.24 -
Insulin 0.110 0.030 <0.01 0.100 <0.01
Other antidiabetic drugs 0.047 0.080 0.57 -

BMI = body mass index, BP = blood pressure, FPG = fasting plasma glucose, HbA1c = glycated hemoglobin

HOMA-R = homeostasis model assessment ratio, HDL-C = high-density lipoprotein cholesterol

LDL-C = low-density lipoprotein cholesterol, Hb = hemoglobin, BNP = brain natriuretic peptide

LVEF = left ventricular ejection fraction, AHI = apnea-hypopnea index, ODI = oxygen desaturation index

SpO2 = peripheral capillary oxygen saturation, DPP-4 = dipeptidyl peptidase-4