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. 2017 Dec 19;12(12):e0189821. doi: 10.1371/journal.pone.0189821

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© 2017 Bharani et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 7 — The novel object recognition task (NORT) was administered 7 days after the LPS injection in control and DSP4-lesioned and non-lesioned rats. Spontaneous locomotion (A) indicates a reduction in movement in the DSP4-lesioned rats compared to both Ctrl and LPS groups. The discrimination index (B) was calculated as the amount of time spent exploring the novel object relative to the familiar object, divided by the total amount of time exploring both objects, and collapsed across all three testing phases. DSP4+LPS-treated rats performed worse on this task compared to the Ctrl group and the LPS group, suggesting that these rats were not able to discriminate between a familiar object and a novel object.