Figure 1.

Common variants and regulatory features at human PLXND1. Four tracks are depicted at the PLXND1 locus. In descending order: WHRadjBMI Variants; 49 variants linked to rs10804591 (European ancestry, 1000G Phase 1, >0.7 R² in linkage disequilibrium of rs10804591). Genes; Havana annotated genes. Arrows within the first exon indicate direction of transcription. All Variants; common variants from 1000 G Phase 1 with a frequency of at least 1% within populations of European ancestry. Regulatory Features; regulation marks predicted by the Ensembl Regulatory Build.⁶⁶ Vertical black bars are 100 kb (A) or 10 kb (B) apart. Brackets in A denote the region shown in B.