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Effects of sertraline on MPT induction in isolated liver mitochondria. Mitochondrial (1.0 mg/ml) was incubated with sertraline (0–100μM) in the presence of 20μM Ca2+. (A) Induction of sertraline on mitochondrial swelling. (B) BA but not cyclosporine A (CsA) protected mitochondrial swelling induced by sertraline. Data are represented as mean from at three independent experiments.
