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. 2017 Nov 3;16(22):2204–2211. doi: 10.1080/15384101.2017.1346754

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© 2017 Jilin University

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Figure 3. — Validation for the expression of significant transcripts by quantitative RT-PCR and ROC analysis of the circRNAs. (A) The expression levels of circZFR are significantly higher than those in corresponding nontumorous tissues. P < 0.001. (B) The expression levels of circFUT8 are significantly higher than those in corresponding nontumorous tissues. P < 0.01. (C) The expression levels of circIPO11 are significantly higher than those in corresponding nontumorous tissues. P < 0.05. (D) The fold change of the circZFR, circFUT8 and circIPO11 expression levels by microarray and qRT-PCR. (E) ROC curve analysis of circZFR, circFUT8 and circIPO11 for discriminative ability between liver cancer cases and normal controls.