Table 2.

Results of mitochondrial respiratory function and image analysis of muscle ultrastructure.

		COPD
	Control	Total	BMIN	BMIL
ST3 (nmol.min−1.mg−1)	18.18 ± 2.65	12.23 ± 3.93	15.10 ± 2.36	8.40 ± 1.49•,★
ST4 (nmol.min−1.mg−1)	3.53 ± 0.29	3.43 ± 0.56	3.79 ± 0.36	2.94 ± 0.38F
RCR (ST3/S T4)	5.13 ± 0.35	3.50 ± 0.71	3.97 ± 0.51▴	2.86 ± 0.32•,★
Number of mitochondria in unit area (n/u −2)	0.52 ± 0.06	0.38 ± 0.08	0.43 ± 0.08	0.32 ± 0.07•
Mean fractional area of mitochondria%	4.31 ± 0.76	3.18 ± 0.75	3.71 ± 0.47	2.5 ± 0.37•,★
Z line width (nm)	103.2 ± 6.42	93.57 ± 9.8	99.8 ± 11.34	87. 2 ± 8.79○

Data are presented as the mean ± SD, unless otherwise stated. BMIN: normal body mass index group; BMIL: low body mass index group; ST3: state 3 respiration; ST4: state 4 respiration; RCR: respiratory control ratio.

^▴: P < 0.01 vs. controls;

^○: P < 0.05,

^•: P < 0.01 vs. controls;

^F: P < 0.05,

^★: P < 0.01 vs. BMIN.