Table S2.
Association of baseline and rate of increase in eGFR (mL/min/1.73 m2) and UACR (mg/g) with LVMI (g/m2) in individuals without heart disease (n = 475) from multiple regression
| Variables | Without Heart Disease N = 475 |
|
|---|---|---|
| β-Coefficient 95% (CI) | P Value | |
| Baseline eGFR | −0.12 (−0.24, 0.01) | .06 |
| Baseline UACR | 2.29 (0.80, 3.77) | .003 |
| Gender (female) | −1.96 (−5.90, 1.98) | .33 |
| BMI | 0.31 (−0.02, 0.65) | .06 |
| Baseline SBP | 0.30 (0.18, 0.42) | <.001 |
| SBP change∗ | 0.26 (0.16, 0.36) | <.001 |
| Rate of increase in eGFR† | −1.04 (−2.00, −0.09) | .03 |
| Rate of increase in UACR‡ | .05 | |
| <0.14 | Reference | |
| 0.14–1.07 | 2.86 (−1.05, 6.77) | .15 |
| ≥1.07 | 4.60 (0.87, 8.33) | .02 |
BMI, body mass index; CI, confidence interval; eGFR, estimated glomerular filtration rate; LVMI, left ventricular mass index; SBP, systolic blood pressure; UACR, urine albumin-to-creatinine ratio.
Analysis was based on model 6 including all covariates and accounted for clustering effect by household as a random effect.
∗
Change in SBP was calculated using SBP at year 7 minus baseline SBP.
†
Rate of increase in eGFR = (eGFR at year 7 − eGFR at baseline)/duration of follow-up (in y).
‡
Rate of increase in UACR = (UACR at year 7 − UACR at baseline)/duration of follow-up (in y).