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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: J Am Chem Soc. 2017 Oct 20;139(43):15460–15466. doi: 10.1021/jacs.7b08775

Figure 4.

Figure 4

Outcome of conjugate addition reactions between protected Dha monomers and aryl boronic acids. Absolute configurations are assigned by comparison to literature data or by analogy (See Supporting Information for details) a. Observation of reversal of enantioselectivity in reactions conducted with and without additive. b. Analysis of the influence of varied cation sources on the outcome of the conjugate addition reaction. c. Demonstration of reversal of enantioselectivity in the presence of varied substrates. d. Synthesis of protected amino esters and amino amides using the Rh-catalyzed conjugate addition methods shown in Fig. 4a. Reactions were conducted with [Rh(cod)2]BF4 in place of [Rh(nbd)2]BF4.