Table 1.

Transmission and viral containment in HIV infected and exposed uninfected infants by TLR9 allele polymorphism.

	HIV+ infants			HEU infants
	TLR9 GA or AA	TLR9 GG	p value	TLR9 GA or AA	TLR9 GG	p value
CMV infection and containment
Ever CMV infected a	100% (19/19)	89% (16/18)	0.1	100% (10/10)	89% (8/9)	0.3
CMV infected by 1 month a	42% (8/19)	11% (2/18)	0.03	20% (2/10)	22% (2/9)	0.9
Median log10 CMV DNA copies/ml (IQR)b	2.4 (2.1–3.1)	2.9 (2.1–3.1)	0.9	2.5 (1.7–3.3)	2.3 (2.1–2.4)	0.8
EBV infection and containment
Ever EBV infected a	69% (24/35)	78% (21/27)	0.4	57% (13/23)	16% (3/19)	0.007
Probability of EBV infection at 12 months [95%CI]c	0.82 [0.64–0.94]	0.67 [0.47–0.85]	0.2	0.67 [0.46–0.86]	0.21 [0.075–0.53]	0.003
Median log10 EBV DNA copies/ml (IQR)b	2.4 (2.0–2.6)	2.8 (2.4–2.9)	0.02	2.1 (1.8–2.5)	1.9 d	*

Notes.

^aChi-square test,

^bMann-Whitney U test,

^cz test comparing infection probabilities at 12 months from Kaplan-Meier model.

^dOnly 1 HEU infant was EBV viremic in the GG group, so comparison was not possible.