Table 3.
Health and economic impact of the aPS intervention (universal ART initiation)§
| Percent of population receiving APS | 12.5% |
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| Health impacts (total population) | |
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| |
| HIV infections averted | 3.7% (1.9–5.6) |
| HIV-related deaths averted | 2.6% (1.6–3.6%) |
| DALYs averted | 1.4% (0.1–2.0) |
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| Health impacts (among aPS partners only) | |
|
| |
| HIV infections averted | 2.6% (−1.3–6.0%) |
| HIV-related deaths averted | 13.7% (10.5–16.3%) |
| DALYs averted | 8.9% (6.7–10.9%) |
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| |
| 5-year incremental aPS intervention costs (per 500,000 adults) | |
|
| |
| Program scenario (millions) | 3.5 (3.2–3.8) |
| Task-shifting scenario (millions) | 2.5 (2.2–2.8) |
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| |
| Cost-effectiveness | |
|
| |
| ICER program scenario ($/DALY averted) | $1,094 ($823–1,619) |
| Percent of program ICERs under Kenya’s per capita GDP out of 200 simulations | 80% |
| ICER task shifting scenario ($/DALY averted) | $833 ($628–1,224) |
| Percent of task-shifting ICERs under Kenya’s per capita GDP out of 200 simulations | 93% |
Values in parentheses represent 90% model variability across 200 simulations (range). Strategies under the threshold of Kenya’s GDP per capita ($1,368) are considered very cost-effective.
Costs and DALYs are discounted at 3% annually. Costs are in 2014 USD.