Table 1.
Antimicrobial activity (μg/mL) of tested phenylthiazoles against MRSA (2658 RCMB).
| |||||
|---|---|---|---|---|---|
| R | MIC (μg/mL) | cpd | R | MIC (μg/mL) | |
| 1b | NA | 2.75 | 19 |
|
1.56 |
| 7 | HN-Me | 12.5 | 20 |
|
3.12 |
| 8 | HN-Et | > 25 | 21 |
|
3.12 |
| 9 | HN-Pr | > 25 | 22 |
|
1.56 |
| 10 | HN-Bu | > 25 | 23 |
|
1.56 |
| 11 |
|
> 25 | 24 |
|
12.5 |
| 12 |
|
> 25 | 25 |
|
> 25 |
| 13 |
|
> 25 | 26 |
|
1.56 |
| 14 |
|
> 25 | 27 |
|
1.17 |
| 15 |
|
> 25 | 28 |
|
> 25 |
| 16 |
|
> 25 | 29 |
|
> 25 |
| 17 |
|
> 25 | 30 |
|
> 25 |
| 18 |
|
12.5 | Vancomycin | N.A. | 1.56 |
N.A. = Not applicable