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. Author manuscript; available in PMC: 2018 Dec 19.
Published in final edited form as: Chem Commun (Camb). 2017 Dec 19;54(1):42–45. doi: 10.1039/c7cc07581b

Figure 3. MERi-SiR inhibits Mer signaling, but with reduced potency.

Figure 3

A) Cell proliferation was measured after 72h treatment. B–D) Western blot (B) and quantification (C–D; normalized as fraction control) show decreased phosphorylation of Mer and downstream Erk1/2 (p44/42 MAPK) following treatment with UNC2025 or MERi-SiR. A–D) Data are means ± S.E.M. using SK-MEL-3; p-values use two-tailed t-tests.