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. 2017 Dec 20;24(6):e494–e502. doi: 10.3747/co.24.3335

TABLE IV.

Univariate and multivariate analyses of young chemotherapy (CTx)–treated breast cancer survivors reporting regular menses at the time of posttreatment anti-Müllerian hormone testing

Predictor Univariate Multivariate


β 95% CI p Value β 95% CI p Value
Attained age −0.042 −0.083 to 0.001 0.042 −0.057 −0.094 to −0.020 0.002
Irregular cycles or amenorrhea during CTxa −0.781 −1.392 to −0.169 0.012 −0.983 −1.548 to −0.417 <0.001
Age at diagnosis −0.050 −0.097 to −0.002 0.041
Body mass index 0.006 −0.033 to 0.046 0.749
Cyclophosphamide use (g/m2) −0.045 −0.16 to 0.079 0.477
Irregular cycles before CTxa 0.607 −0.361 to 1.58 0.219
Irregular cycles after CTxa −0.404 −0.904 to −0.096 0.114
Tamoxifen exposure 0.256 −0.268 to 0.780 0.338
Trastuzumab exposure 0.592 0.067 to 1.116 0.027
Years after CTx −0.015 −0.086 to 0.056 0.67
a

Referenced against regular menstrual cycles.

CI = confidence interval.