TABLE IV.
Predictor | Univariate | Multivariate | ||||
---|---|---|---|---|---|---|
|
|
|||||
β | 95% CI | p Value | β | 95% CI | p Value | |
Attained age | −0.042 | −0.083 to 0.001 | 0.042 | −0.057 | −0.094 to −0.020 | 0.002 |
Irregular cycles or amenorrhea during CTxa | −0.781 | −1.392 to −0.169 | 0.012 | −0.983 | −1.548 to −0.417 | <0.001 |
Age at diagnosis | −0.050 | −0.097 to −0.002 | 0.041 | — | — | |
Body mass index | 0.006 | −0.033 to 0.046 | 0.749 | — | — | |
Cyclophosphamide use (g/m2) | −0.045 | −0.16 to 0.079 | 0.477 | — | — | |
Irregular cycles before CTxa | 0.607 | −0.361 to 1.58 | 0.219 | — | — | |
Irregular cycles after CTxa | −0.404 | −0.904 to −0.096 | 0.114 | — | — | |
Tamoxifen exposure | 0.256 | −0.268 to 0.780 | 0.338 | — | — | |
Trastuzumab exposure | 0.592 | 0.067 to 1.116 | 0.027 | — | — | |
Years after CTx | −0.015 | −0.086 to 0.056 | 0.67 | — | — |
Referenced against regular menstrual cycles.
CI = confidence interval.