Table 1.
Baseline demographics of all patients and those with normal systolic function on day 1
| Variable | All patients (62) | Normal ejection fraction on day 1 N = 44 (71%) |
||
|---|---|---|---|---|
| Normal diastolic function (n = 11) | Abnormal diastolic dysfunction (n = 20) | Indeterminate diastolic function (n = 13) | ||
| Demographics | ||||
| Age | 63.1 ± 12.4 | 55 ± 14 | 67 ± 8* | 62 ± 12 |
| Sex (M) | 35 (56%) | 6 (55%) | 6 (30%) | 6 (46%) |
| Past medical history | ||||
| IHD | 19 (31%) | 0 | 3 (15%) | 5 (38%) |
| Diabetes | 20 (32%) | 3 (27%) | 5 (25%) | 4 (31%) |
| HTN | 37 (60%) | 4 (36%) | 6 (30%) | 6 (46%) |
| Previous documented diastolic dysfunction | 6 (10%) | 0 | 3 (15%) | 2 (15%) |
| Previous documented systolic dysfunction | 5 (8%) | 1 (9%) | 0 | 0 |
| CRF | 11 (18%) | 0 | 5 (25%) | 3 (23%)** |
| Clinical data | ||||
| Mechanical ventilation D1 (n) | 44 (71%) | 7 (64%) | 13 (65%) | 9 (69%) |
| Mechanical ventilation D3 | 32 (52%) | 6 (55%) | 8 (40%) | 9 (69%) |
| Total noradrenaline at first echo (ml) | 155 (51, 330) | 49 (15, 162) | 129 (47, 330) | 202 (111,573) |
| HR day 1 | 97 ± 21 | 97 ± 25 | 91 ± 17 | 101 ± 14 |
| Arrhythmia D1 | 13 (21%) | 2 (18%) | 4 (20%) | 2 (15%) |
| SOFA D1 | 10 ± 3.7 | 9.5 ± 4 | 9.9 ± 3.9 | 9.1 ± 3.7 |
| PEEP D1 | 8 (5, 10) | 10 (5, 14) | 8 (6, 10) | 8 (5,9) |
Diastolic dysfunction assessed by 2016 ASE/EACVI guidelines
p values not given unless significant, *p < 0.018; **p < 0.021