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Comparison of Bacille Calmette-Guérin (BCG), MTBVAC, and H37Rv properties.
| BCG | MTBVAC | H37RV | |
|---|---|---|---|
| Source | Virulent M. bovis | Virulent M. tuberculosis | Reference lab strain |
| Attenuation process | Subcultivation | Deletions in phoP and fadD26 virulence genes | None |
| Number of epitopes | • • | • • • | • • • |
| Immunogenicity | • | • • • | • • • |
| Protection | • • | • • • | |
| Attenuation/safety | • • • | • • • | |
