Table 16.

Diseases and functions associated with networks identified by IPA to be affected by observed mutations in COA/UAB-6.

ID	Molecules in network	Diseases and functions associated with this network
1	AHNAK2, ARFGAP2, ARHGAP28, ATXN2, BMP2, BPHL, C11orf73, C4orf27, CEBPB, CYSLTR1, ERK, EVC2, FOXP3, GH1, GPR126, GPR137, GPR146, GPR160, GPRC5C, HNF4A, LRRC40, NFkB (complex), NMUR1, NMUR2, NPFF, NUP62, Orm, POLR3E, PTGES, PTPRK, Srrm1, TMEM176A, UTP3, VN1R1, ZNF71	Carbohydrate metabolism, small molecule biochemistry, tissue morphology
2	APP, ARMC9, BOD1, C18orf21, C3orf36, C5orf15, C9orf41, C9orf142, CDK5RAP2, CHAC2, CHID1, CRY2, DDHD2, EEPD1, GIMAP4, HEATR5A, HINT2, HINT3, LRRC42, MMGT1, NENF, NME8, PUS7L, PYROXD1, RAB43, RABL3, RNASE11, TBCC, TOMM5, UBC, UTP23, VWA5A, WDR88, WDR45B, ZNF720	Developmental disorders, neurological diseases