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MLPA BRCAness phenotype of breast cancer cell lines analysed.
| Breast cancer cell line | Phenotype | |
|---|---|---|
| BRCA1_like | Sporadic_like | |
| MCF7 | NO (0.02664) | YES (0.97336) |
| MDA-MB-231 | NO (0.01184) | YES (0.98816) |
| MDA-MB-436 | NO (0.00125) | YES (0.99875) |
| MDA-MB-468 | YES (0.97079) | NO (0.02921) |
| HCC70 | YES (0.99405) | NO (0.00595) |
The cut-off value to classify a cell line as BRCA1-like was set at 0.5. Below this value, the cell line was classified as sporadic-like.
