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. 2017 Dec 19;4:2. doi: 10.1038/s41540-017-0038-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Pan-cancer correlations between the eigengenes of the informative signatures and the sample activity profiles. In a, the distribution of the conservation scores for the Informative (black) and the remaining signatures (red) is reported. In b, the dependence between informative gene sets overlap (Jaccard-index) and average correlation between the meta-samples defined by the informative gene sets is reported. Each point corresponds to an informative signature and their color is proportional to the point density: from red (high density) to blue (low density)