Table 3. Diagnostic accuracy of the TB-LAMP compared with culture.

Indicators	Overall	Smear-positive	Smear-negative
Sensitivity (95% CI)	83.6 (72.9–90.6)	92.0 (81.2–96.8)	58.8 (36.0–78.4)
Specificity (95% CI)	100 (NA)	-	-
PPV (95% CI)	100 (NA)	-	-
NPV (95% CI)	94.6 (91.1–96.8)	-	-

Twenty-eight culture-negative samples that were positive by both TB-LAMP and real-time PCR were excluded from the analysis.

Abbreviations: TB-LAMP, loop-mediated isothermal amplification assay; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value; NA, not available.