Figure 5.

Afh mutants show higher timing uncertainty compared to control mice. (a) Representation of the Switch task in Experiment 1. Pellet-rewards are associated with two different lateral hoppers, based on the duration of the signal (e.g., short-signal (S) for left hopper and long-signals (L) for right hopper, counterbalanced). 20% of short- (S) and long- (L) signal trials were not rewarded (Probe trials, S_p and L_p, respectively). All cumulative distribution functions, CDFs, of switch latencies are plotted for wild-type (n = 6) and Afh mutants (n = 6) for the dark phase (blue and red, respectively) and light phase (light blue and light red, respectively) in LD (b) and DD (c). The boxplots of the coefficient of variations (CV) and timing accuracy (TA) of switch latencies are plotted above and below the curves, respectively. In DD condition, values are computed for the subjective night (D) and subjective day (L).