Table 4.

Oxidation of sulfide catalyzed by 1-Mn ^a

Entry	R	Catalyst	Conv. (%)b	Yield (%)c	ee (%)d
1	Ph	1-Mn	99	93	92 (S)
2e	Ph	Homo	71	67	0
3	4-MePh	1-Mn	99	93	92 (S)
4e	4-MePh	Homo	63	59	0
5	4-MeOPh	1-Mn	95	92	84 (S)
6e	4-MeOPh	Homo	80	75	0
7	4-ClPh	1-Mn	96	94	89 (S)
8	3-FPh	1-Mn	98	91	87 (S)

^a Reaction conditions: 10 (0.1 mmol), (S)-1-Mn (2 mol % catalyst based on MOF), 1.2 equiv. aqueous H₂O₂ in DCE (0.8 mL), −30 °C, 4 h. No over-oxidized sulfone byproducts were detected

^b Determined by ¹H NMR analysis

^c Isolated yield

^d Determined by chiral HPLC analysis (letters in brackets specify the excess isomer)

^e A 1:1 mixture of MnCl₂ ·4H₂O and (S)-Me₂ L (6 mol% catalyst based on Mn) was used as the catalyst