. 2017 Sep 18;34(12):2532–2540. doi: 10.1007/s11095-017-2251-y

Table I.

Panel of Test Compounds for Permeability Evaluation

Compound	Log P	MW (Da)	Ka _{in vivo} (min⁻¹)
Dextran 10 K	-	10,000	0.00007 ⁽²⁾
Mannitol	−3.1	182	0.011 ⁽³⁾
Terbutaline	0.1	274	0.06 ⁽¹⁾
Formoterol	1.1	840	0.19 ⁽¹⁾
Metoprolol	1.9	684	0.58 ⁽¹⁾
Propranolol	3.0	259	-
Imipramine	4.4	316	0.53 ⁽¹⁾

In vivo Ka data are from (1) ref. [22], (2) ref. [23] and (3) ref. [24]