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. 2017 May 24;34(12):2466–2476. doi: 10.1007/s11095-017-2176-5

Table I.

Summary of inclusion/exclusion criteria and elevated profile parameters

Parameter Inclusion criteria
Healthy cell inclusion criteria % cells > mean – 2nd SD mitochondrial activity
Normal nuclear area % cells > mean nuclear area - 2nd SD and < mean + 2nd SD of the untreated cell population
Elevated mitochondrial activity % cells > mean mitochondrial activity +2nd SD of the untreated cell population
Elevated membrane permeability % cells > mean membrane permeability +2nd SD of the untreated cell population
Elevated cellular area % cells > mean cell area + 2nd SD of the untreated cell population
Elevated nuclear/cellular area ratio % cells > mean nuclear/cell area ratio + 2nd SD of the untreated cell population
Elevated vacuole number per cell % cells > mean vacuole number per cell +2nd SD of the untreated cell population
Elevated vacuole area per cell % cells > mean vacuole area per cell +2nd SD of the untreated cell population
Elevated phospholipid content % cells > mean phospholipid content per cell +2nd SD of the untreated cell population
Elevated neutral lipid content % cells > mean neutral lipid content per cell +2nd SD of the untreated cell population