TABLE 1.

GBS gene products conditionally essential for survival in human blood and corresponding ESSENTIALS Log₂ FC values

Gene locus	Gene producta	Log2 FC
SAK_1262	Regulatory protein CpsA	−7.34
SAK_1255	Capsular polysaccharide synthesis protein CpsH	−6.24
SAK_1251	Polysaccharide biosynthesis protein CpsL	−5.65
SAK_0483	R3H domain-containing protein	−5.64
SAK_1254	Capsular polysaccharide biosynthesis protein	−5.42
SAK_1259	Tyrosine-protein kinase CpsD	−5.23
SAK_1260	Capsular polysaccharide biosynthesis protein CpsC	−5.15
SAK_1249	UDP-N-acetylglucosamine-2-epimerase NeuC	−5.03
SAK_1900	GTP pyrophosphokinase RelA	−4.97
SAK_1895	PTS system transporter subunit IIA	−4.92
SAK_1258	Glycosyl transferase CpsE	−4.83
SAK_1253	Capsular polysaccharide biosynthesis protein CpsJ	−4.76
SAK_1248	NeuD protein	−4.70
SAK_0186	IgA-binding β antigen	−4.38
SAK_1256	Polysaccharide biosynthesis protein CpsG	−4.36
SAK_1257	Polysaccharide biosynthesis protein CpsF	−4.32

^aThe products of genes in the capsular polysaccharide locus are in boldface.