TABLE 2.

Gene set enrichment analysis for KEGG classes significantly differently expressed at baseline or following stringent response activation in 10/84 and A909

Strain(s) and condition, KEGG class downregulated	No. of hits	Class size	P value	Adjusted P value	Description
10/84 vs A909 at baseline
330	6	12	6.10E−06	0.00011	Arginine and proline metabolism: arcA, argF, arc, argG, SAK_2064 (putative duplicated arcC), SAK_2065 (putative duplicated argF)
500	6	35	5.20E−03	0.03334	Starch and sucrose metabolism
790	3	8	5.60E−03	0.03334	Folate biosynthesis
920	2	3	7.40E−03	0.03334	Sulfur metabolism
190	2	4	1.40E−02	0.04309	Oxidative phosphorylation
A909 under SRa
330	2	12	0.021	0.037	Arginine and proline metabolism: arcA, argF
564	2	6	0.005	0.024	Glycerophospholipid metabolism
640	2	10	0.015	0.034	Propanoate metabolism
650	2	7	0.007	0.024	Butanoate metabolism
1084 under SR
220	2	9	0.0017	0.0017	Arginine biosynthesis: arcA, glnA
240	6	42	<1E−12	<1E−12	Pyrimidine metabolism
250	4	13	<1E−12	<1E−12	Alanine, aspartate, and glutamate metabolism

^aSR, stringent response.