TABLE 3.
Participant summary by community functional subtype (F1, F2, and F3)
| Parameter | Value for group |
P value comparing all groupsf | P value for F3 vs F2f | ||
|---|---|---|---|---|---|
| F1 (n = 74) | F2 (n = 51) | F3 (n = 35) | |||
| No. (%) of participants at location | 0.02 | 0.8 | |||
| CPT | 31 (42) | 32 (63) | 23 (66) | ||
| JHB | 43 (58) | 19 (37) | 12 (34) | ||
| Median age (yr)a | 18 | 19 | 19 | 0.24 | |
| Median pHb | 4.7 | 5 | 5 | 4.00e−06 | 0.8 |
| No. (%) of participants with HPV status | 0.05 | 0.7 | |||
| High risk | 21 (28) | 24 (57) | 19 (54) | ||
| Low risk | 19 (26) | 13 (26) | 6 (17) | ||
| Negative | 34 (46) | 14 (27) | 10 (29) | ||
| No. (%) of participants with BV status | <2.2e−16 | 0.003 | |||
| BV positive | 8 (11) | 32 (63) | 33 (94) | ||
| BV intermediate | 6 (8) | 11 (21) | 1 (3) | ||
| BV negative | 60 (81) | 8 (16) | 1 (3) | ||
| No. (%) of participants of compositional subtypec | <2.2e−16 | 3.00e−04 | |||
| C1 | 0 (0) | 35 (85) | 35 (100) | ||
| C2 | 32 (44) | 0 (0) | 0 (0) | ||
| C3 | 41 (56) | 6 (15) | 0 (0) | ||
| Median Nugent score | 0 | 8 | 10 | <2.2e−16 | 1.00e−04 |
| No. (%) of participants with STI | |||||
| Any | 17 (23) | 29 (57) | 19 (54) | 1.00e−04 | 0.8 |
| C. trachomatis | 13 (18) | 20 (39) | 16 (46) | 0.003 | 0.7 |
| No. (%) of participants of inflammatory categoryd | 4.00e−12 | 1.00e−04 | |||
| High | 21 (29) | 34 (69) | 35 (100) | ||
| Low | 51 (71) | 15 (31) | 0 (0) | ||
| Median BMIe | 22.5 | 23.3 | 25.8 | 0.0001 | 1 |
| Median α diversity value (Shannon) | 1 | 2.3 | 2.3 | <2.2e−16 | 0.8 |
| No. (%) of participants using HC | 48 (65) | 38 (76) | 28 (80) | 0.2 | 0.8 |
Eight women had missing information.
Six women had missing information.
Eleven women were not classified as belonging to C1/C2/C3 (i.e., clustering criteria were not met).
Four women had missing information.
Seven women had missing information.
Significant adjusted P values are in boldface type.