FIG 3.

PE and TP administration improved the HFD-induced glucose metabolism disorder. Mice were fasted overnight (12 h), and an OGTT (A) was performed after a glucose gavage (1 g/kg body weight). (B) Area under the concentration-time curve (AUC) for the OGTT. The mice were fasted overnight (12 h) for the fasting glucose and fasting INS (D) determination at 0 and 12 weeks; fasting glucose changes (C) and HOMA-IR index (G) were calculated. PE and TP significantly enhanced the mRNA expression of liver Glut4 (E) and G6pc (F). The data are expressed as the means ± SEM; n = 8 to 10 (A, B, C, D, G) or n = 6 (E, F). Data with different lowercase letters are significantly different (P < 0.05) according to the post hoc one-way ANOVA statistical analysis. Asterisks indicate a significant difference between two groups using the unpaired two-tailed Student t test (*, P < 0.05; **, P < 0.01).