FIG 7.

Characterization of innate immune cell populations in lungs of WT and NLRP3 KO C57BL/6 mice infected with M. pneumoniae S1 for 2 days. Lungs from mock-infected or S1-infected WT and NLRP3 KO C57BL/6 mice were harvested, digested, and analyzed by fluorescence-activated cell sorting. Identified cell populations include total neutrophils (A), activated neutrophils (B), dendritic cells (C), and inflammatory macrophages (D). Cell populations in infected lungs were normalized to mock-infected cell populations by subtracting values of the uninfected controls from those of the infected animals. *, P < 0.05; **, P < 0.01.