Skip to main content
. 2017 Dec 19;86(1):e00381-17. doi: 10.1128/IAI.00381-17

FIG 6.

FIG 6

The inhibitory actions of OG1RF_11271 and OG1RF_11272 are limited in the presence of IreK. (A) The cholate and lysozyme resistance of the WT E. faecalis strain (OG1RF) and the ΔireK (CK119), ΔOG1RF_11271 (IB18), ΔOG1RF_11272 (IB19), and ΔOG1RF_11271 ΔOG1RF_11272 (IB20) mutants was determined. The reported MICs represent the median values from three independent biological replicates. (B) The cholate and lysozyme resistance of the WT E. faecalis strain (OG1RF) and the ΔireK mutant (CK119) carrying the empty vector (pJRG9) or expressing wild-type copies of the indicated genes was determined. (C) CPRG hydrolysis was measured for the strains listed in panel B. The reported measurements represent averages from three independent cultures, and error bars represent standard deviations. Statistical significance was evaluated by t test. ****, P < 0.0001.