FIG 7 .

Increased bacterial attachment to lung tissue from Slc6a14^−/y (knockout) mice. (A) Tissue explants from wild-type and Slc6a14^−/y mice were exposed to P. aeruginosa for 2 h, and bacterial attachment was quantified by counting CFU. Cage- and age-matched pairings indicate significantly greater attachment of bacteria to lung explants from Slc6a14^−/y mice. Data points represent biological replicates ± the standard deviation. Asterisks indicate a P value of 0.0452 (one-tailed paired t test). (B) Intimate attachment of P. aeruginosa (white arrows) visualized by scanning electron microscopy in tracheal segments exposed to bacteria for 2 h. Scale bar, 5 μm.