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. 2017 Dec 15;11:390. doi: 10.3389/fncel.2017.00390

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Copyright © 2017 Juzekaeva, Nasretdinov, Gainutdinov, Sintsov, Mukhtarov and Khazipov.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Various patterns of AD initiation and propagation in barrel cortex. (A) Microphotograph of a barrel cortex slice in DIC-IR (left) and OIS snapshots at different time points after OGD induction. Below, the corresponding AD fronts are presented as the OIS first derivative. Bottom left panel shows time color coded AD front contours plotted at 3 s intervals. Note that AD is initiated in one barrel and further propagates preferentially through L4. (B) Similar example of AD which is initiated in a barrel located in the middle of the imaging window and which collides with another AD wave arriving from another locus on the right of the imaging window. (C) Example of AD propagating preferentially through layer 4 from the left side of the imaging window. (D) Example of AD propagating from the left and right sides and colliding in the middle of the imaging window in L4.