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. 2017 Dec 15;11:390. doi: 10.3389/fncel.2017.00390

Figure 4.

Figure 4

AD propagation after surgical cut above, below and through L4. (A–C) Example microphotographs of the barrel cortex slices in DIC-IR (left) with the cuts made above (A), below (B), and through (C) the layer 4 and OIS snapshots at different time points after OGD induction. Below, the corresponding AD fronts are presented as the OIS first derivative. Bottom left panel shows time color coded SD front contours plotted at 3 s intervals. Note that AD waves invade supragranular and infragranular layers in all cases but AD emerges earlier if connection with L4 is preserved. AD propagation to L2/3 above the cut on panel (A) was too slow and is truncated on the contour map. See Video 5 for the entire AD wave in this experiment.