Table 1.
Baseline Characteristics of 6,808 MESA Participants Overall and Stratified by Quartiles of High-Attenuation Areas
| Overall | HAA |
||||
|---|---|---|---|---|---|
| Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | ||
| HAA %, range | 2–75% | 2.0–3.5% | 3.5–4.2% | 4.2–5.4% | 5.4–75.2% |
| Participants, n | 6,808 | 1,702 | 1,702 | 1,702 | 1,702 |
| Age, yr | 62 ± 10 | 62 ± 10 | 62 ± 10 | 62 ± 10 | 63 ± 10 |
| Male sex | 3,213 (47) | 952 (56) | 839 (49) | 750 (44) | 672 (39) |
| Race/ethnicity | |||||
| White | 2,622 (38) | 942 (55) | 666 (39) | 586 (34) | 428 (25) |
| African American | 1,892 (28) | 385 (23) | 481 (28) | 524 (31) | 502 (29) |
| Hispanic | 1,495 (22) | 238 (14) | 349 (21) | 394 (23) | 514 (30) |
| Chinese | 804 (12) | 138 (8) | 207 (12) | 200 (12) | 259 (15) |
| BMI, kg/m2 | 28 ± 5 | 27 ± 5 | 28 ± 5 | 29 ± 6 | 30 ± 6 |
| Height, cm | 166 ± 10 | 169 ± 10 | 167 ± 10 | 166 ± 10 | 164 ± 10 |
| Weight, kg | 79 ± 17 | 75 ± 16 | 78 ± 17 | 81 ± 18 | 80 ± 18 |
| Waist circumference, cm | 98 ± 14 | 94 ± 13 | 97 ± 14 | 100 ± 14 | 101 ± 15 |
| Hip circumference, cm | 106 ± 11 | 103 ± 10 | 105 ± 11 | 107 ± 12 | 108 ± 12 |
| Smoking history | |||||
| Never-smokers | 3,085 (45) | 707 (42) | 744 (43) | 786 (46) | 848 (50) |
| Former smokers | 2,761 (41) | 785 (46) | 724 (43) | 645 (38) | 607 (36) |
| Current smokers | 967 (14) | 211 (12) | 235 (14) | 273 (16) | 248 (15) |
| Cigarette pack-years* | 14.5 (3–33) | 13 (3–32) | 15 (4–34) | 16 (4–34) | 14 (3–31) |
| Spirometry† | |||||
| FVC, L | 3.19 ± 0.95 | 3.63 ± 0.94 | 3.26 ± 0.90 | 3.04 ± 0.89 | 2.85 ± 0.92 |
| FVC, % predicted | 95 ± 16 | 102 ± 16 | 96 ± 15 | 93 ± 18 | 91 ± 17 |
| FEV1, L | 2.38 ± 0.73 | 2.61 ± 0.74 | 2.43 ± 0.71 | 2.30 ± 0.70 | 2.20 ± 0.72 |
| FEV1, % predicted | 94 ± 18 | 98 ± 19 | 94 ± 18 | 92 ± 18 | 92 ± 18 |
| FEV1/FVC ratio | 0.75 ± 0.09 | 0.72 ± 0.09 | 0.75 ± 0.09 | 0.75 ± 0.08 | 0.77 ± 0.07 |
| Computed tomography | |||||
| Total imaged lung volume, ml | 2,691 (2,208–3,253) | 3,312 (2,857–3,861) | 2,866 (2,449–3,362) | 2,569 (2,201–3,006) | 2,045 (1,711–2,466) |
| Emphysema, % | 4.2 (3.5–5.4) | 6.7 (3.8–10.1) | 3.6 (2.1–6.0) | 2.3 (1.3–4.0) | 0.9 (0.4–1.9) |
Definition of abbreviations: BMI = body mass index; HAA = high-attenuation areas; MESA = Multi-Ethnic Study of Atherosclerosis.
Data are presented as mean ± SD, n (%), or median (interquartile range), unless otherwise stated. All parameters collected at MESA baseline visit in 2000–2002, unless otherwise stated.
*
Among ever-smokers.
†
Completed at MESA exam 3–4 (years 2004–2006) in 3,832 MESA participants.