Table 1.
Characteristics of patient cohort
Characteristic | Number | Percentage |
---|---|---|
Age, y | ||
Age range | 16-70 | |
Median age | 49 | |
Sex | ||
Male | 58 | 51 |
Female | 55 | 49 |
Cytogenetic risk stratification | ||
Favorable risk | 5 | 4 |
Intermediate risk | 85 | 75 |
Adverse risk | 22 | 20 |
Unknown | 1 | 1 |
Disease status at transplant | ||
CR1 | 78 | 69 |
CR2 | 27 | 24 |
Not in CR | 8 | 7 |
Relapse posttransplant | 49 | 43 |
Transplant conditioning | ||
Reduced intensity | 75 | 66 |
Myeloablative | 38 | 34 |
Conditioning regimen | ||
Flu/Mel/Campath | 58 | 51 |
Cy/TBI | 29 | 26 |
Flu/Mel | 9 | 8 |
Flu/Cy/TBI | 5 | 4 |
Bu/Cy | 5 | 4 |
FLAMSA/TBI/ATG | 3 | 3 |
FLAMSA/Bu/ATG | 1 | 1 |
TBI/Flu/Cy/ATG | 1 | 1 |
Cy/TBI/Campath | 1 | 1 |
Bu/Flu/Thio/ATG | 1 | 1 |
Donor source | ||
Sibling | 49 | 43 |
Unrelated | 61 | 54 |
Cord | 3 | 3 |
CMV recipient/donor | ||
Negative/Negative | 44 | 39 |
Positive/Positive | 33 | 29 |
Positive/Negative | 25 | 22 |
Negative/Positive | 11 | 10 |
Equivocal/Negative | 1 | 1 |
Status at last contact | ||
Alive | 61 | 54 |
Dead | 52 | 46 |
ATG, antithymocyte globulin; Bu, busulfan; CMV, cytomegalovirus; Cy, cyclophosphamide; FLAMSA, fludarabine, cytarabine, amsacrine, cyclosphosphamide; Flu, fludarabine; Mel, melphalan; Thio, thiotepa; TBI, total body irradiation.