Table 2.
Drug class | Number of drugs | Number of targets | Number of direct interacting genes |
---|---|---|---|
Anticoagulants | 5 | 4 | 31 |
ACE inhibitors | 9 | 6 | 37 |
Angiotensin II receptor blockers (or Inhibitors) | 5 | 3 | 37 |
ARNIs | 1 | 1 | 1 |
Antiplatelet agents | 4 | 5 | 4 |
Beta-adrenergic blocking agents | 8 | 6 | 13 |
Calcium channel blockers | 7 | 30 | 42 |
Cholesterol-lowering medications | 5 | 9 | 69 |
Combined alpha and beta-blockers | 2 | 14 | 57 |
Digoxin | 1 | 1 | 8 |
Diuretics | 8 | 44 | 60 |
Vasodilators | 5 | 11 | 11 |