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. 2017 Jun 16;45(14):8378–8391. doi: 10.1093/nar/gkx521

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© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Effect of compounds 1 and 2 on mitochondrial membrane potential (Ψ_m) of T. b. brucei s427-WT. The results shown are the mean of three independent determinations; error bars depict standard errors. The inset table lists the P values, using a Student's two-tailed, unpaired t-test comparing each category to the untreated control, incubated for the same length of time; a value <0.05 is considered to be significant. Untreated cells (drug free), valinomycin (negative - depolarization) and troglitazone (positive - hyperpolarization) are employed as controls.