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. 2017 Aug 16;45(17):10190–10205. doi: 10.1093/nar/gkx720

Figure 7.

Figure 7.

A possible model for RT backtracking and recovery. The anchor domain (AD) contacts the template, in ssDNA form, ∼8 bp ahead of the fork. This interaction modulates both the rate of elongation and the rate of entering a backtracked state by RT. Upon backtracking, the hairpin reanneals, thus making the recovery time dependent on the fork dynamics.